Novobiocine [Inn-French]
Brand names,
Novobiocine [Inn-French]
Analogs
Novobiocine [Inn-French]
Brand Names Mixture
- Albacillin Suspension (Novobiocin (Novobiocin Sodium) + Penicillin G Procaine)
- Delta-Albaplex Tablets (Novobiocin (Novobiocin Sodium) + Prednisolone + Tetracycline Hydrochloride)
- Novodry Plus Suspension (Novobiocin (Novobiocin Sodium) + Penicillin G Procaine)
- Special Formula 17900-Forte Suspension (Dihydrostreptomycin (Dihydrostreptomycin Sulfate) + Hydrocortisone Acetate + Hydrocortisone Sodium Succinate + Novobiocin (Novobiocin Sodium) + Penicillin G Procaine + Polymyxin B Sulfate)
Novobiocine [Inn-French]
Chemical_Formula
C31H36N2O11
Novobiocine [Inn-French]
RX_link
No information avaliable
Novobiocine [Inn-French]
fda sheet
Novobiocine [Inn-French]
msds (material safety sheet)
Novobiocine [Inn-French]
Synthesis Reference
No information avaliable
Novobiocine [Inn-French]
Molecular Weight
612.624 g/mol
Novobiocine [Inn-French]
Melting Point
No information avaliable
Novobiocine [Inn-French]
H2O Solubility
Insoluble
Novobiocine [Inn-French]
State
Solid
Novobiocine [Inn-French]
LogP
2.737
Novobiocine [Inn-French]
Dosage Forms
Drug premix; Suspension
Novobiocine [Inn-French]
Indication
For the treatment of infections due to staphylococci and other susceptible organisms
Novobiocine [Inn-French]
Pharmacology
Novobiocin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses.
Novobiocine [Inn-French]
Absorption
No information avaliable
Novobiocine [Inn-French]
side effects and Toxicity
No information avaliable
Novobiocine [Inn-French]
Patient Information
No information avaliable
Novobiocine [Inn-French]
Organisms Affected
Enteric bacteria and other eubacteria